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CAT 2017 Slot 1 — VARC Question 29

Mixed PracticeEasy

The five sentences (labelled 1, 2, 3, 4, 5) given in this question, when properly sequenced, from a coherent paragraph. Each sentence is labelled with a number. Decide on the proper order for the sentences and key in this sequence of five numbers as your answer.

  1. Scientists have for the first time managed to edit genes in a human embryo to repair a genetic mutation, fuelling hopes that such procedures may one day be available outside laboratory conditions.
  2. The cardiac disease causes sudden death in otherwise healthy young athletes and affects about one in 500 people overall.
  3. Correcting the mutation in the gene would not only ensure that the child is healthy but also prevents transmission of the mutation to future generations.
  4. It is caused by a mutation in a particular gene and a child will suffer from the condition even if it inherits only one copy of the mutated gene.
  5. In results announced in Nature this week, scientists fixed a mutation that thickens the heart muscle, a condition called hypertrophic cardiomyopathy.

Answer & solution

Correct answer: 15243

Answer: 15243

Solution

Easy

Five-sentence para-jumble (key in the order). Spot the only sentence that can open (a self-contained announcement), then follow the chain of specifics — each later sentence narrows down or refers back to the disease introduced earlier.

1

Opener: 1. Sentence 1 is the only general, self-standing statement — scientists edited genes in a human embryo “for the first time” to repair a genetic mutation. Every other sentence assumes the disease/result is already on the table, so 1 starts.

2

1–5. Sentence 5 specifies the announcement (“In results announced in Nature this week”) and names the actual mutation fixed — one that thickens the heart muscle, hypertrophic cardiomyopathy. It elaborates the “repair” of sentence 1: 1–5.

3

5–2. Sentence 2 describes “The cardiac disease” — the very condition just named in 5 — noting it kills young athletes and affects one in 500. The definite article points back to 5: 1–5–2.

4

2–4. Sentence 4 opens “It is caused by a mutation …” — “it” = the cardiac disease of sentence 2, explaining its genetic cause (one mutated copy suffices): 1–5–2–4.

5

Closer: 3. Sentence 3 concludes the payoff — correcting the mutation makes the child healthy and prevents transmission to future generations. It follows naturally after the cause is stated in 4: 1 – 5 – 2 – 4 – 3.

Correct sequence: 15243.

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CAT 2017 Slot 1 VARC Q29: The five sentences (labelled 1, 2, 3, 4, 5) given in this question, when properly sequenced, from a coherent p — Solution | TheCATExam